Oxygenation in COPD patient
I have been once asked by my supervisor during my first week of posting: why we need to maintain SpO2 of COPD patient lower than 92% but not higher??
So, here's the explanation:
Because in normal individual increase CO2 will triggers our respiratory drive, however COPD patient is having Type 2 respiratory failure due to chronic accumulation of CO2 in their blood and the response of increase CO2 that trigger the respiratory centre is blunt, so their body actually maintain the respiratory homeostasis by the decrease of oxygen level ( hypoxic drive)
Giving sudden high oygenation therapy will ceased the hypoxic drive in the patient thus causing hypoventilation and lead to carbon dioxide rentention.
Ideal Spo2 in COPD patient : 88-92%
Some other theories also explained the phenomenon such as Haldane effect and V/Q mismatch.
So, here's the explanation:
Because in normal individual increase CO2 will triggers our respiratory drive, however COPD patient is having Type 2 respiratory failure due to chronic accumulation of CO2 in their blood and the response of increase CO2 that trigger the respiratory centre is blunt, so their body actually maintain the respiratory homeostasis by the decrease of oxygen level ( hypoxic drive)
Giving sudden high oygenation therapy will ceased the hypoxic drive in the patient thus causing hypoventilation and lead to carbon dioxide rentention.
Ideal Spo2 in COPD patient : 88-92%
Some other theories also explained the phenomenon such as Haldane effect and V/Q mismatch.
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